KRT10-specific Antibody
Rabbit Polyclonal
Catalog number: 16855-1-AP
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Applications
| Tested applications | ELISA, IHC |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive IHC detected in | human lung cancer |
| Recommended dilution | IHC: 1:100-1:500 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Immunohistochemistry of paraffin-embedded human lung cancer using 16855-1-AP(KRT10-specific Antibody) at Dilution 1:200 (under 10x lens)
Immunohistochemistry of paraffin-embedded human lung cancer using 16855-1-AP(KRT10-specific Antibody) at Dilution 1:200 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | keratin 10 |
|
Calculated molecular weight |
59kd |
Observed molecular
weight |
|
|
GenBank accession number |
NM_000421 | Gene ID (NCBI) | 3858 |
| Gene symbol | KRT10 | Synonyms | CK10; K10; KPP |
Background
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. As a type I keratin, keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia. This antibody is specifically against KRT10. |
