KRT7-Specific Antibody
Rabbit Polyclonal
Catalog number: 17513-1-AP
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Applications
| Tested applications | ELISA, WB, IHC, IF |
| Cited applications | IF |
| Species specificity | human; other species not tested. |
| Cited species | |
| Positive WB detected in | HeLa cells, HepG2 cells |
| Positive IHC detected in | human lung cancer |
| Positive IF detected in | HepG2 cells |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:20-1:200 IF: 1:20-1:50 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HeLa cells were subjected to SDS PAGE followed by western blot with 17513-1-AP(KRT7-Specific Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using 17513-1-AP(KRT7-Specific Antibody) at Dilution 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human lung cancer using 17513-1-AP(KRT7-Specific Antibody) at Dilution 1:50 (under 40x lens)
Immunofluorescent analysis of HepG2 cells, using KRT7 antibody 17513-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | keratin 7 |
|
Calculated molecular weight |
51kd |
Observed molecular
weight |
54kd |
|
GenBank accession number |
NM_005556 | Gene ID (NCBI) | 3855 |
| Gene symbol | KRT7 | Synonyms | CK7; K2C7; K7; MGC129731; MGC3625; SCL |
Background
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT7 is a type II keratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. This antibody is specifically against KRT7. |
