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LYSMD3 Polyclonal antibody

LYSMD3 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 24313-1-AP

Synonyms

LYSMD3



Tested Applications

Positive WB detected inNeuro-2a cells
Positive IHC detected inhuman liver tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:5000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 24313-1-AP is LYSMD3 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen LYSMD3 fusion protein Ag19430
Full Name LysM, putative peptidoglycan-binding, domain containing 3
Calculated Molecular Weight 306 aa, 35 kDa
Observed Molecular Weight 35 kDa
GenBank Accession NumberBC136741
Gene Symbol LYSMD3
Gene ID (NCBI) 116068
RRIDAB_2879490
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

LYSMD3 also termed as LysM and putative peptidoglycan binding domain containing protein 3 is a 306 amino acid single-pass membrane protein that contains one LysM repeat. LysM domain encoding genes may play a role in brain and in nervous system development and functioning. LYSMD3, shows a high level of central nervous expression during embryogenesis and is also, therefore, a good candidate gene for other central nervous system (CNS) symptoms, such as psychomotor retardation, brain anomalies and muscular hypotonia of the 5q14.3 microdeletion syndrome.

Protocols

Product Specific Protocols
WB protocol for LYSMD3 antibody 24313-1-APDownload protocol
IHC protocol for LYSMD3 antibody 24313-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle

J Biol Chem

LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens.

Authors - Christine C Yokoyama
humanWB

Mol Biol Cell

Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response.

Authors - Yevgeniy V Serebrenik
humanWB

Cell Rep

LYSMD3: A mammalian pattern recognition receptor for chitin.

Authors - Xin He
  • KO Validated