MZB1 Antibody
Rabbit Polyclonal
Catalog number: 11454-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC |
| Species specificity | human; other species not tested. |
| Cited species | human |
| Positive WB detected in | Raji cells |
| Positive IHC detected in | human gliomas |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Raji cells were subjected to SDS PAGE followed by western blot with 11454-1-AP(MZB1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gliomas using 11454-1-AP(MZB1 Antibody) at Dilution 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | MZB1 fusion protein ag2015 | Full name | hypothetical protein MGC29506 |
|
Calculated molecular weight |
189aa,21kd |
Observed molecular
weight |
19-21kd |
|
GenBank accession number |
BC021275 | Gene ID (NCBI) | 51237 |
| Gene symbol | MGC29506 | Synonyms | FLJ32987; PACAP |
Background
MZB1, also named as ,PACAP, MGC29506 and pERp1, belongs to the PERP1 family. It is associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. MGC29506(PACAP) may exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. (PubMed: 11350957) MZB1 has 5 isoforms with MW 21kd and 7-13kd. |
