MGLL Antibody
Rabbit Polyclonal
Catalog number: 14986-1-AP
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Applications
| Tested applications | ELISA, IHC |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive IHC detected in | human liver cancer |
| Recommended dilution | IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Immunohistochemistry of paraffin-embedded human liver cancer using 14986-1-AP(MGLL Antibody) at Dilution 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human liver cancer using 14986-1-AP(MGLL Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | MGLL fusion protein ag6970 | Full name | monoglyceride lipase |
|
Calculated molecular weight |
33kd |
Observed molecular
weight |
|
|
GenBank accession number |
BC000551 | Gene ID (NCBI) | 11343 |
| Gene symbol | MGLL | Synonyms | HU-K5; HUK5; MGL |
Background
MGLL(monoglyceride lipase) is also named as MAGL, HU-K5 and belongs to the monoacylglycerol lipase family. It converts monoacylglycerides to free fatty acids and glycerol and functions together with hormone-sensitive lipase (HSL) in the mobilization of fatty acids from the triglyceride stores of adipocytes. MGL prootein is ubiquitously expressed in kidney, spleen, heart, liver, stomach, brain, lung, adrenal gland, adipose tissue and in brain,there are two bands of 33 kDa and 35 kDa can be detected. The single protein species expressed in muscle is larger(around 40 kDa).(PMID:11470505). This protein can exsit as a homodimer(PMID:19957260). This antibody is specific to MGLL. |
