MIER3 Antibody
Rabbit Polyclonal
Catalog number: 17543-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | mouse uterus tissue |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse uterus tissue were subjected to SDS PAGE followed by western blot with 17543-1-AP(MIER3 Antibody) at dilution of 1:600
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | MIER3 fusion protein ag11604 | Full name | mesoderm induction early response 1, family member 3 |
|
Calculated molecular weight |
522aa,59kd |
Observed molecular
weight |
55kd |
|
GenBank accession number |
BC041348 | Gene ID (NCBI) | 166968 |
| Gene symbol | MIER3 | Synonyms | DKFZp686L09111; DKFZp781G1119; DKFZp781I1119; FLJ35954 |
Background
The mesoderm induction early response (MIER) protein family is known as fibroblast growth factor (FGF)-regulated immediate-early protein family. Activated by FGF, MIER proteins may have a pivotal role in FGF-regulated cellular activities, indicating a potential influence in the progression of certain cancers [PMID:15117948]. MIER3 localizes to the nucleus and primarily functions as a transcriptional repressor. Rat mammary carcinoma susceptibility 1b (Mcs1b) is a quantitative trait locus on RN02 that confers decreased susceptibility when Copenhagen (COP)-resistant alleles are introgressed into a Wistar Furth (WF)-susceptible genome. MIER3 is a candidate Mcs1b gene [PMID:22993404]. |
