MMP3 Antibody
Rabbit Polyclonal
Catalog number: 17873-1-AP
Ask a question about this product click here
Loading price...
Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse, rabbit |
| Positive WB detected in | A549 cells, A2780 cells, HeLa cells, human skeletal muscle tissue |
| Positive IHC detected in | human breast cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
A549 cells were subjected to SDS PAGE followed by western blot with 17873-1-AP(MMP3 Antibody) at dilution of 1:1200
Immunohistochemistry of paraffin-embedded human breast cancer using 17873-1-AP(MMP3 Antibody) at Dilution 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human breast cancer using 17873-1-AP(MMP3 Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | MMP3 fusion protein ag12359 | Full name | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
|
Calculated molecular weight |
477aa,54kd |
Observed molecular
weight |
45-47kd |
|
GenBank accession number |
BC074869 | Gene ID (NCBI) | 4314 |
| Gene symbol | MMP3 | Synonyms | CHDS6; MGC126102; MGC126103; MGC126104; MMP-3; SL-1; STMY; STMY1; STR1 |
Background
Matrix metalloproteinases (MMPs) play a critically important role in extracellular matrix remodeling and have been implicated in a number of key normal and pathologic processes.These proteases have come to represent important therapeutic and diagnostic targets for the treatment and detection of human cancers. MMP-3 activate procollagenase via two pathways: slow direct activation and rapid activation in conjunction with tissue or plasma proteinases. |
