MYB Antibody
Rabbit Polyclonal
Catalog number: 17800-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | HL-60 cells |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HL-60 cells were subjected to SDS PAGE followed by western blot with 17800-1-AP(MYB Antibody) at dilution of 1:600
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | MYB fusion protein ag12021 | Full name | v-myb myeloblastosis viral oncogene homolog (avian) |
|
Calculated molecular weight |
640aa,72kd |
Observed molecular
weight |
72-80kd |
|
GenBank accession number |
BC064955 | Gene ID (NCBI) | 4602 |
| Gene symbol | MYB | Synonyms | Cmyb; c-myb; c-myb_CDS; efg |
Background
The MYB protein is a transcription factor that plays a key role in regulating the proliferation/differentiation of progenitor cells in bone marrow, colonic crypts, and neurogenic niches [PMID:18574464]. It is involved in the regulation of epithelial-to-mesenchymal transition (EMT) and invasion in neuroblastoma, colon carcinoma, and embryonic kidney cells through the upregulation of the transcription repressor Slug [PMID:20622260]. It also a DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3', and plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. |
