Marcks Antibody
Rabbit Polyclonal
Catalog number: 10004-2-Ig
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IF, IHC, IP, WB |
| Species specificity | human, mouse; other species not tested. |
| Cited species | bovine, human, mouse, rat |
| Positive WB detected in | mouse brain tissue |
| Positive IHC detected in | human prostate cancer |
| Recommended dilution | WB: 1:1000-1:10000 IHC: 1:100-1:500 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with 10004-2-Ig(Marcks Antibody) at dilution of 1:3000
Immunohistochemistry of paraffin-embedded human prostate cancer using 10004-2-Ig(Marcks Antibody) at Dilution 1:200 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Protein A purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Recombinant Protein | Full name | myristoylated alanine rich protein kinase C substrate |
|
Calculated molecular weight |
39kd |
Observed molecular
weight |
88kd |
|
GenBank accession number |
BC046601 | Gene ID (NCBI) | 17118 |
| Gene symbol | Marcks | Synonyms | Macs; PKCSL |
Background
MARCKS is a member of MARCKS family of PKC substrate and it is also a widely accepted indicator of PKC activation. It shows a ubiquitous tissue distribution. The calculated molecular weight of MARCKS is 39 kDa and its apparent molecular weights were found at 68 kDa to 90 kDa in different species. This protein is a known to regulated cytoskeleton remodeling and membrane recycling. The anti-MARCKS antibody is raised against purified MARCKS protein from mouse brain using a method similar to that previously reported for MacMARCKS |
