Marcksl1 Antibody
Rabbit Polyclonal
Catalog number: 10002-2-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | IF, IHC, WB |
| Species specificity | human, mouse; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | mouse brain tissue |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with 10002-2-AP(Marcksl1 Antibody) at dilution of 1:500
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Recombinant Protein | Full name | MARCKS-like 1 |
|
Calculated molecular weight |
40kd |
Observed molecular
weight |
60kd |
|
GenBank accession number |
BC006757 | Gene ID (NCBI) | 17357 |
| Gene symbol | Marcksl1 | Synonyms | AL022768; AW215397; AW536807; D4Bc1; F52; MacMARCKS; Macs-2; Macs-3; Macs2; Macs3; Mlp; Mrp |
Background
MacMARCKS is a member of MARCKS family of PKC substrate. It is widely used in the signal transduction studies as an indictor of PKC activation. The protein has a calculated molecular weight of 20 kDa and an apparent molecular weight of 42-45 kDa in different species on SDS PAGE. MacMARCKS functions in many aspects of cell physiology including integrin activation, cell spreading and phagocytosis. Its functions are though to associate with its ability in binding and regulating actin and microtubule cytoskeleton. Current evidence indicated that this protein also involved controls membrane fluidity and molecular mobility of membrane proteins |
