NEB-Specific Antibody
Rabbit Polyclonal
Catalog number: 19706-1-AP
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Applications
| Tested applications | ELISA, IHC |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive IHC detected in | human skeletal muscle |
| Recommended dilution | IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Immunohistochemistry of paraffin-embedded human skeletal muscle using 19706-1-AP(NEB-Specific Antibody) at Dilution 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human skeletal muscle using 19706-1-AP(NEB-Specific Antibody) at Dilution 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | nebulin |
|
Calculated molecular weight |
773kd |
Observed molecular
weight |
|
|
GenBank accession number |
NM_004543 | Gene ID (NCBI) | 4703 |
| Gene symbol | NEB | Synonyms | DKFZp686C1456; FLJ11505; FLJ36536; FLJ39568; FLJ39584; NEB177D; NEM2 |
Background
NEB, a giant muscle protein, may be involved in maintaining the structural integrity of sarcomeres and the membrane system associated with the myofibrils. NEB binds and stabilizes F-actin. Defects in NEB are the cause of nemaline myopathy type 2 (NEM2). The antibody is specific to NEB. |
