NMB Antibody
Rabbit Polyclonal
Catalog number: 10888-1-AP
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Applications
| Tested applications | ELISA, IHC |
| Cited applications | IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | chimpanzees, human, monkey |
| Positive IHC detected in | human breast cancer |
| Recommended dilution | IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Immunohistochemistry of paraffin-embedded human breast cancer using 10888-1-AP(NMB Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | NMB fusion protein ag0842 | Full name | neuromedin B |
|
Calculated molecular weight |
16kd |
Observed molecular
weight |
|
|
GenBank accession number |
BC007407 | Gene ID (NCBI) | 4828 |
| Gene symbol | NMB | Synonyms | MGC17211; MGC2277; MGC3936 |
Background
Neuromedin B (NMB) is a bombesin-like peptide, which inhibits food intake and modulates stress-related behaviour. It exerts its function via NMB receptor (NMB-R). NMB is encoded in a 76-amino acid precursor. The mature NMB was reported to be a 10-amino-acid peptide, giving two bands of 1.2 kDa and 1.5 kDa in western blotting. NMB is expressed in brain, gastrointestinal tract, pancreas, adrenals, and adipose tissue. It regulates exocrine and endocrine secretions, cell growth, body temperature and blood pressure and glucose level in vivo. |
