NOX1 Antibody
Rabbit Polyclonal
Catalog number: 17772-1-AP
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Applications
| Tested applications | ELISA |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | NOX1 fusion protein ag12187 | Full name | NADPH oxidase 1 |
|
Calculated molecular weight |
564aa,65kd |
Observed molecular
weight |
|
|
GenBank accession number |
BC075014 | Gene ID (NCBI) | 27035 |
| Gene symbol | NOX1 | Synonyms | GP91-2; MOX1; NOH-1; NOH1 |
Background
NOX1(NADPH oxidase 1) is also named as MOX1, NOH1 and belongs to the reactive oxygen species (ROS)-generating NADPH oxidase family. It plays a role in host defense, cell growth and differentiation, cell migration, and malignant transformation(PMID:20351171). It also can mediate oncogenic Ras-induced upregulation of VEGF and angiogenesis by activating Sp1 through Ras-ERK-dependent phosphorylation of Sp1(PMID:18454179). It has 3 isoforms produced by alternative splicing with the molecular weight of 65 kDa, 22 kDa and 59 kDa. The full length protein has two glycosylation sites. This antibody is specific to NOX1. |
