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Tested Applications
| Positive WB detected in | fetal human brain tissue, rat brain tissue, mouse brain tissue |
| Positive IHC detected in | human brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | A549 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 4 publications below |
Product Information
11999-1-AP targets TrkC in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | TrkC fusion protein Ag2635 Predict reactive species |
| Full Name | neurotrophic tyrosine kinase, receptor, type 3 |
| Calculated Molecular Weight | 839 aa, 94 kDa |
| Observed Molecular Weight | 94 kDa |
| GenBank Accession Number | BC013693 |
| Gene Symbol | TrkC |
| Gene ID (NCBI) | 4916 |
| RRID | AB_2155428 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q16288 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
TrkC (Tropomyosin Receptor Kinase C), also known as NTRK3 (Neurotrophic Tyrosine Kinase Receptor Type 3), belongs to the Trk family of receptor tyrosine kinases, which also includes TrkA and TrkB. These receptors are primarily involved in the development and function of the nervous system.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for TrkC antibody 11999-1-AP | Download protocol |
| IHC protocol for TrkC antibody 11999-1-AP | Download protocol |
| IF protocol for TrkC antibody 11999-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Front Cell Dev Biol Identification of New miRNA-mRNA Networks in the Development of Non-syndromic Cleft Lip With or Without Cleft Palate. | ||
Stem Cell Res Ther NT3P75-2 gene-modified bone mesenchymal stem cells improve neurological function recovery in mouse TBI model. | ||
iScience Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice. | ||
Transl Androl Urol Whole body vibration training promotes proprioceptive pathway for the treatment of stress urinary incontinence in rats |
