NUS1 Antibody
Rabbit Polyclonal
Catalog number: 15986-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | mouse liver tissue, mouse kidney tissue, mouse pancreas tissue |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with 15986-1-AP(NUS1 Antibody) at dilution of 1:800
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | NUS1 fusion protein ag8789 | Full name | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) |
|
Calculated molecular weight |
293aa,33kd |
Observed molecular
weight |
30-32kd |
|
GenBank accession number |
BC013026 | Gene ID (NCBI) | 116150 |
| Gene symbol | NUS1 | Synonyms | C6orf68; MGC117249; MGC7199; MGC:7199; NgBR |
Background
Nogo proteins containing three isoforms (Nogo A,B,C) have been implicated in a variety of critical cellular processes including CNS neuronal regeneration, vascular cell spreading and chemotaxis. While only two functional receptors have been reported so far: NgR binding all three Nogos and NgBR specifically binding Nogo-B. Nogo-B also known as NgBR or NUS1, specifically binds the amino amino terminus (residues 1-200) of Nogo-B, the interaction of which is essential for stimulating chemotaxis, morphogenesis and angiogenesis.Western blot analysis detected high Ngbr expression in mouse heart, liver, kidney, and pancreas with molecular weight around 30 kD. |
