OLIG2 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 13999-1-AP

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Freight/Packing

Size: 09µ/gram

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Species specificity:
Human, Mouse, Rat

Positive WB detected in:
human brain tissue, mouse brain tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human gliomas tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:200-1:2000
IP : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.

Immunogen Information


Full name:
oligodendrocyte lineage transcription factor 2

Calculated molecular weight:
32 kDa

Observed molecular weight:
32 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
OLIG2

Synonyms
BHLHB1, bHLHe19, OLIG2, OLIGO2, PRKCBP2, RACK17
Background

OLIG2, also named as BHLHB1, BHLHE19, PRKCBP2 and RACK17, is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1, OLIG2 establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. OLIG2 is widely expressed in subsets of glia cells and progenitors, and it is strongly induced at different sites by both acute and chronic injury, albeit with different mechanisms. OLIG2 acts as a repressor of neurogenesis in cells reacting to brain injury. It may represent an effective approach towards evoking neuronal repair from parenchymal precursors.(PMID:19390819 )


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