PCK2 Antibody
Rabbit Polyclonal
Catalog number: 14892-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | human brain tissue, human colon tissue |
| Positive IHC detected in | human breast cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human brain tissue were subjected to SDS PAGE followed by western blot with 14892-1-AP(PCK2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using 14892-1-AP(PCK2 Antibody) at Dilution 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human breast cancer using 14892-1-AP(PCK2 Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | PCK2 fusion protein ag6681 | Full name | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
|
Calculated molecular weight |
71kd |
Observed molecular
weight |
71kd |
|
GenBank accession number |
BC001454 | Gene ID (NCBI) | 5106 |
| Gene symbol | PCK2 | Synonyms | PEPCK; PEPCK-M; PEPCK2 |
Background
PCK2(phosphoenolpyruvate carboxykinase [GTP], mitochondrial) is also named as PEPCK2, PEPCK-M and belongs to the phosphoenolpyruvate carboxykinase [GTP] family. It catalyses the irreversible conversion of oxaloacetate to phosphoenolpyruvate, an important initial step in hepatic gluconeogenesis.Defects in PCK2 are the cause of mitochondrial phosphoenolpyruvate carboxykinase deficiency (M-PEPCKD). It has 2 isoforms produced by alternative splicing with the molecular weight of 71 kDa and 48 kDa. This antibody is specific to PCK2. |
