PFKFB2 Antibody
Rabbit Polyclonal
Catalog number: 17838-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | human heart tissue, mouse brain tissue, rat brain tissue |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human heart tissue were subjected to SDS PAGE followed by western blot with 17838-1-AP(PFKFB2 Antibody) at dilution of 1:500
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | PFKFB2 fusion protein ag12181 | Full name | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
|
Calculated molecular weight |
505aa,58kd |
Observed molecular
weight |
58 kDa, 110 kDa |
|
GenBank accession number |
BC075076 | Gene ID (NCBI) | 5208 |
| Gene symbol | PFKFB2 | Synonyms | DKFZp781D2217; MGC138308; MGC138310; PFK-2/FBPase-2 |
Background
PFKFB2(6-Phosphofructo-2-kinase/fructose 2,6-bisphosphatase 2) is also named as PFK-2/FBPase-2, which is a bifunctional enzyme responsible for the synthesis and breakdown of Fru-2,6-P2, a key metabolite in the regulation of glycolysis(PMID:10095107). In the C-terminal section, it belongs to the phosphoglycerate mutase family.The enzyme is a dimer of identical subunits, each composed of 505 amino acids and containing three discrete domains(PMID: 2552438). It has 2 isoforms produced by alternative splicing. This antibody is specific to PFKFB2. |
