PPIB Antibody
Rabbit Polyclonal
Catalog number: 11607-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IF, IHC, WB |
| Species specificity | human, mouse; other species not tested. |
| Cited species | human, monkey, mouse |
| Positive WB detected in | Raji cells, HeLa cells, HepG2 cells, human skin tissue, mouse liver tissue, NIH/3T3 cells, U-937 cells, Recombinant protein |
| Positive IHC detected in | human lymphoma |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Raji cells were subjected to SDS PAGE followed by western blot with 11607-1-AP(PPIB Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human lymphoma using 11607-1-AP(PPIB Antibody) at Dilution 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human lymphoma using 11607-1-AP(PPIB Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | PPIB fusion protein ag2161 | Full name | peptidylprolyl isomerase B (cyclophilin B) |
|
Calculated molecular weight |
216aa,24kd |
Observed molecular
weight |
24 kDa |
|
GenBank accession number |
BC032138 | Gene ID (NCBI) | 5479 |
| Gene symbol | PPIB | Synonyms | CYP-S1; CYPB; MGC14109; MGC2224; SCYLP |
Background
PPIB, also named as CYPB, SCYLP, PPIase B and CYP-S1, belongs to the cyclophilin-type PPIase family and PPIase B subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIB is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes. |
