PRDX1 Antibody
Rabbit Polyclonal
Catalog number: 15816-1-AP
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Applications
| Tested applications | ELISA, WB, IF |
| Cited applications | WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | HEK-293 cells, A549 cells, HeLa cells, HepG2 cells, MCF7 cells, mouse kidney tissue, NIH/3T3 cells, Raji cells, rat kidney tissue, RAW264.7 cells |
| Positive IF detected in | HepG2 cells |
| Recommended dilution | WB: 1:500-1:5000 IF: 1:20-1:50 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with 15816-1-AP(PRDX1 Antibody) at dilution of 1:1000
Immunofluorescent analysis of HepG2 cells, using PRDX1 antibody 15816-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | PRDX1 fusion protein ag8602 | Full name | peroxiredoxin 1 |
|
Calculated molecular weight |
199aa,22kd |
Observed molecular
weight |
23 kDa |
|
GenBank accession number |
BC007063 | Gene ID (NCBI) | 5052 |
| Gene symbol | PRDX1 | Synonyms | MSP23; NKEFA; PAG; PAGA; PAGB; PRX1; PRXI; TDPX2 |
Background
PRDX1(Peroxiredoxin-1) is a thiol reductase that plays critical roles in oxidative and thermal stress defense mechanisms through its abilities to metabolize H2O2 and act as a molecular chaperone, respectively.PRDX1 also reduces intramolecular cystine bridges .It can form a dimer(PMID:22583657).It also can be phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity(PMID:11986303).This antibody is specific to this antibody. |
