QSOX1 Antibody
Rabbit Polyclonal
Catalog number: 12713-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | SW 1990 cells, HeLa cells, human heart tissue, human placenta tissue, MCF7 cells, mouse heart tissue, HT-1080 cells |
| Recommended dilution | WB: 1:500-1:5000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
SW 1990 cells were subjected to SDS PAGE followed by western blot with 12713-1-AP(QSOX1 Antibody) at dilution of 1:1000
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | QSOX1 fusion protein ag3396 | Full name | quiescin Q6 sulfhydryl oxidase 1 |
|
Calculated molecular weight |
747aa,83kd |
Observed molecular
weight |
65-94 kDa |
|
GenBank accession number |
BC017692 | Gene ID (NCBI) | 5768 |
| Gene symbol | QSOX1 | Synonyms | FLJ34858; Q6; QSCN6 |
Background
QSOX1(Sulfhydryl oxidase 1) catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.It has two isoforms with the molecular weight of 67 kda and 83 kDa,respectively. It is detected a band of 95 Kda in HT1080 cell lines (PMID:17331072).Isoform 1 is expressed on golgi apparatus membrane and isoform 2 is secreted(PMID:10708601).This antibody is specific to this protein. The isoform1(QSOX1a) is the full length of QSOX1, approximately 78 kd; and the isoform2(QSOX1b) is the splicing form, approximately 62kd(PMID:14633699; 2496424). QSOX1 is highly expressed in tumor cell lines but is not expressed in adjacent normal cells(PMID:21989104). |
