RCC1 Antibody
Rabbit Polyclonal
Catalog number: 22142-1-AP
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Applications
| Tested applications | ELISA, WB, IP |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | HeLa cells, HEK-293 cells, A431 cells, COS-7 cells, HepG2 cells, Jurkat cells, NIH/3T3 cells, SH-SY5Y cells |
| Recommended dilution | WB: 1:500-1:5000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
IP result of anti-RCC1 (22142-1-AP for IP and Detection) with 293 cell.
HeLa cells were subjected to SDS PAGE followed by western blot with 22142-1-AP(RCC1 Antibody) at dilution of 1:1000
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | RCC1 fusion protein ag17569 | Full name | regulator of chromosome condensation 1 |
|
Calculated molecular weight |
421aa,45kd |
Observed molecular
weight |
45-50kd |
|
GenBank accession number |
BC010067 | Gene ID (NCBI) | 1104 |
| Gene symbol | RCC1 | Synonyms | CHC1; RCC1-I |
Background
CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1. |
