RCVRN Antibody
Rabbit Polyclonal
Catalog number: 10073-1-AP
Ask a question about this product click here
Loading price...
Applications
| Tested applications | ELISA, WB, IF |
| Cited applications | IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, rat |
| Positive WB detected in | mouse eye tissue, mouse eye tissue |
| Positive IF detected in | MCF-7 cells |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse eye tissue were subjected to SDS PAGE followed by western blot with 10073-1-AP(RCVRN Antibody) at dilution of 1:600
Immunofluorescent analysis of MCF-7 cells, using 10073-1-AP and Rhodamine-labeled goat anti-rabbit IgG (red).
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | RCVRN fusion protein ag0119 | Full name | recoverin |
|
Calculated molecular weight |
24kd |
Observed molecular
weight |
23kd |
|
GenBank accession number |
BC001720 | Gene ID (NCBI) | 5957 |
| Gene symbol | RCVRN | Synonyms | RCV1 |
Background
Recoverin, belonging to a family of the neuronal calcium sensor (NCS) proteins, has a restricted expression in retinal photoreceptors or neurons or neuroendocrine cells. It has been suggested to play a role in light and dark adaptation by regulating rhodopsin phosphorylation. Recently, it has been found that autoantibodies against recoverin (24 kDa) have been strongly associated with cancer -associated retinopathy (CAR) syndrome, a paraneoplastic disease of the retina. But functions of recoverin in cancer cells remain unknown. |
