RIPK1-Specific Antibody
Rabbit Polyclonal
Catalog number: 17519-1-AP
Ask a question about this product click here
Loading price...
Applications
| Tested applications | ELISA, WB, IP |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | NIH/3T3 cells, K-562 cells, UV treated HeLa cells |
| Recommended dilution | WB: 1:200-1:1000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
IP result of anti-RIPK1 (17519-1-AP for IP and Detection) with Hela cell.
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 17519-1-AP(RIPK1-Specific Antibody) at dilution of 1:300
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
|
Calculated molecular weight |
76kd |
Observed molecular
weight |
74 kDa |
|
GenBank accession number |
NM_003804 | Gene ID (NCBI) | 8737 |
| Gene symbol | RIPK1 | Synonyms | FLJ39204; RIP; RIP1 |
Background
RIPK1(Receptor-interacting serine/threonine-protein kinase 1) is primarily involved in mediating TNF-R1-induced cell activation, apoptosis and necroptosis and belongs to a novel class of kinases thatfunction in cell survival and cell death mechanisms(PMID:22685397 ).It has 2 isoforms produced by alternative splicing.It also can exist as the protein with lower molecular weight about 25kd and 45kd in HAEC and HUVEC(PMID:22685397).This antibody is specific to RIPK1. |
