SDCBP2 Antibody
Rabbit Polyclonal
Catalog number: 10407-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | mouse brain tissue, human liver tissue, mouse heart tissue |
| Positive IHC detected in | human breast cancer |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with 10407-1-AP(SDCBP2 Antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human breast cancer using 10407-1-AP(SDCBP2 Antibody) at Dilution 1:50 (under 25x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | SDCBP2 fusion protein ag0668 | Full name | syndecan binding protein (syntenin) 2 |
|
Calculated molecular weight |
31.6 kda |
Observed molecular
weight |
35-37kd |
|
GenBank accession number |
BC002727 | Gene ID (NCBI) | 27111 |
| Gene symbol | SDCBP2 | Synonyms | FLJ12256; SITAC18; ST-2 |
Background
Syndecan-binding protein 2 (SDCBP2, Syntenin 2) is a protein containing two PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins. SDCBP2 binds with high affinity to PIP2 and is targeted to the plasma membrane, nucleoli and nuclear speckles via its PDZ domains (PMID: 15961997). SDCBP2 exists in two alternatively spliced variants, 2α and 2β, which differ in the lengths of their N-terminal regions. (PMID: 15276154) |
