SERPINE2 Antibody
Rabbit Polyclonal
Catalog number: 11303-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | A549 cells, MCF7 cells, rat heart tissue |
| Positive IHC detected in | human pancreas cancer |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
A549 cells were subjected to SDS PAGE followed by western blot with 11303-1-AP(SERPINE2 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human pancreas cancer using 11303-1-AP(SERPINE2 Antibody) at Dilution 1:50 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | SERPINE2 fusion protein ag1830 | Full name | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
|
Calculated molecular weight |
44kd |
Observed molecular
weight |
44-50kd |
|
GenBank accession number |
BC015663 | Gene ID (NCBI) | 5270 |
| Gene symbol | SERPINE2 | Synonyms | GDN; PI7; PN1; PNI |
Background
SERPINE2 also called protease nexin-1 and glial-derived neurite promoting factor, is a 44-kDa member of the serine protease inhibitor (SERPIN) superfamily. It would be a potent inhibitor of the urokinase-plasminogen activator (uPA), tissue-type PA (tPA), thrombin, trypsin, factor XIa, and prostasin. SERPINE2 is widely expressed in various tissues, including endothelial cells, fibroblasts, smooth muscle cells, tumor cells, glial cells, neurons, and placental cells. |
