URAT1 Antibody
Rabbit Polyclonal
Catalog number: 14937-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | PC-13 cells, HEK-293 cells, HepG2 cells, human kidney tissue |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
PC-13 cells were subjected to SDS PAGE followed by western blot with 14937-1-AP(URAT1 Antibody) at dilution of 1:600
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | URAT1 fusion protein ag6770 | Full name | solute carrier family 22 (organic anion/urate transporter), member 12 |
|
Calculated molecular weight |
60kd |
Observed molecular
weight |
65-70kd or 40kd |
|
GenBank accession number |
BC053348 | Gene ID (NCBI) | 116085 |
| Gene symbol | SLC22A12 | Synonyms | OAT4L; RST; URAT1 |
Background
Human urate anion exchanger (URAT1), also known as SLC22A12, is a urate transporter located in the proximal tubules of human kidney and responsible for urate reabsorption. Defects in gene encoding URAT1 cause hypouricemia renal type 1 (RHUC1). This antibody recognizes the native and glycosylated URAT1 between 65 and 70 kDa as well as the truncated 40kDa protein. |
