SLC25A13 Antibody
Rabbit Polyclonal
Catalog number: 10789-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | Raji cells, HEK-293 cells, A431 cells, mouse kidney tissue, mouse liver tissue, Raji cells |
| Positive IHC detected in | human colon cancer |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Raji cells were subjected to SDS PAGE followed by western blot with 10789-1-AP(SLC25A13 Antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human colon cancer using 10789-1-AP(SLC25A13 Antibody) at Dilution 1:100 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | SLC25A13 fusion protein ag1242 | Full name | solute carrier family 25, member 13 (citrin) |
|
Calculated molecular weight |
74kd |
Observed molecular
weight |
60-63kd |
|
GenBank accession number |
BC006566 | Gene ID (NCBI) | 10165 |
| Gene symbol | SLC25A13 | Synonyms | ARALAR2; CITRIN; CTLN2 |
Background
SLC25A13, also known as citrin, has been identified as a mitochondrial aspartate–glutamate carrier protein and may be implicated in metabolic compartmentation. It consists of 675 amino acid residues and harbors four EF-hands and six mitochondrial transmembranous (TM) spanners. Mutations in SLC25A13 gene cause adult-onset type II citrullinemia (CTLN2) and neonatal intrahepatic cholestasis ((NICCD). The complete deletion or cleaved SLA25A13 proteins have been reported in patients with SLC25A13 mutation. |
