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SOX1 Polyclonal antibody

SOX1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 20744-1-AP

Synonyms

SOX1, Transcription factor SOX 1

Validation Data Gallery

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  • Western Blot (WB) analysis of NCCIT cells using SOX1 Polyclonal antibody (20744-1-AP)

    WB analysis of NCCIT using 20744-1-AP

    NCCIT cell were subjected to SDS PAGE followed by western blot with 20744-1-AP (SOX1 Antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours.

Tested Applications

Positive WB detected inNCCIT cell

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 1 publications below

Product Information

20744-1-AP targets SOX1 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name SRY (sex determining region Y)-box 1
Calculated Molecular Weight 39 kDa
Observed Molecular Weight 45-50 kDa
GenBank Accession NumberNM_005986
Gene Symbol SOX1
Gene ID (NCBI) 6656
RRIDAB_2878732
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX1 may function as a switch in neuronal development and Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.

Protocols

Product Specific Protocols
WB protocol for SOX1 antibody 20744-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

J Cell Mol Med

Down-regulation of exosomal miR-200c derived from keratinocytes in vitiligo lesions suppresses melanogenesis.

Authors - Chaoshuai Zhao
View Article