SPRR3 Antibody
Rabbit Polyclonal
Catalog number: 11742-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC, WB |
| Species specificity | human; other species not tested. |
| Cited species | human |
| Positive WB detected in | HeLa cells, human liver tissue |
| Positive IHC detected in | human colon cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HeLa cells were subjected to SDS PAGE followed by western blot with 11742-1-AP(SPRR3 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using 11742-1-AP(SPRR3 Antibody) at Dilution 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human colon cancer using 11742-1-AP(SPRR3 Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | SPRR3 fusion protein ag2337 | Full name | small proline-rich protein 3 |
|
Calculated molecular weight |
19kd |
Observed molecular
weight |
22-25kd |
|
GenBank accession number |
BC017802 | Gene ID (NCBI) | 6707 |
| Gene symbol | SPRR3 | Synonyms |
Background
SPRR3, also named as Esophagin, Cornifin beta and SPRC, belongs to the cornifin (SPRR) family. It is cross-linked envelope protein of keratinocytes. Increased expression of SPRR3 appears to be involved in colorectal tumorigenesis. SPRR3 is a marker for terminal squamous cell differentiation.a potential novel therapeutic target for less advanced stages of Breast Cancer. |
