TRAPA, SSR1 Antibody
Rabbit Polyclonal
Catalog number: 10583-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IF, WB |
| Species specificity | human; other species not tested. |
| Cited species | rat |
| Positive WB detected in | human liver tissue |
| Positive IHC detected in | human ovary tumor |
| Recommended dilution | WB: 1:200-1:1000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human liver tissue were subjected to SDS PAGE followed by western blot with 10583-1-AP(TRAPA, SSR1 Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human ovary tumor using 10583-1-AP(TRAPA, SSR1 Antibody) at Dilution 1:100 (under 25x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | TRAPA, SSR1 fusion protein ag0878 | Full name | signal sequence receptor, alpha |
|
Calculated molecular weight |
34kd |
Observed molecular
weight |
34kd |
|
GenBank accession number |
BC007710 | Gene ID (NCBI) | 6745 |
| Gene symbol | SSR1 | Synonyms | DKFZp781N23103; FLJ14232; FLJ22100; FLJ23034; FLJ78242; FLJ93042; TRAPA |
Background
TRAPA (translocon-associated protein subunit alpha), also known as SSR1 (signal sequence receptor subunit alpha), is a 34-kDa single-spanning membrane glycoprotein of the endoplasmic reticulum (ER) (PMID: 8050590). It is a part of the tetrameric TRAP complex (TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma) which functions in regulating the retention of ER resident proteins (PMID: 7916687). The TRAP complex is also involved in endoplasmic reticulum-associated degradation (ERAD) (PMID: 17380188). |
