STAT5B Antibody
Rabbit Polyclonal
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human; other species not tested. |
| Cited species | |
| Positive WB detected in | K-562 cells |
| Recommended dilution | WB: 1:500-1:5000 |
IP = Immunoprecipitation
K-562 cells were subjected to SDS PAGE followed by western blot with 51072-2-AP(STAT5B Antibody) at dilution of 1:1500
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
| Immunogen | Peptide | Full name | signal transducer and activator of transcription 5B |
|
Calculated molecular weight |
90kd |
Observed molecular
weight |
91kd |
|
GenBank accession number |
BC065227 | Gene ID (NCBI) | 6777 |
| Gene symbol | STAT5B | Synonyms | STAT5 |
STAT5B belongs to the transcription factor STAT family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B carries out a dual function: signal transduction and activation of transcription. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This antibody is specific to STAT5B. It has no cross reaction to STAT5A. |
