STMN3 AntibodyRabbit Polyclonal
|Tested applications||ELISA, WB, IHC, IP|
|Species specificity||human, mouse, rat; other species not tested.|
|Positive WB detected in||mouse brain tissue, human brain tissue, rat brain tissue|
|Positive IHC detected in||human colon cancer|
|Recommended dilution||WB: 1:1000-1:10000|
IP = Immunoprecipitation
- IP result of anti-STMN3 (11311-1-AP for IP and Detection) with mouse brain tissue lysate.
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 11311-1-AP(STMN3 Antibody) at dilution of 1:2000
- Immunohistochemistry of paraffin-embedded human colon cancer using 11311-1-AP(STMN3 Antibody) at Dilution 1:50 (under 10x lens)
|Source||Rabbit||Purification method||Antigen affinity purification|
|Isotype||IgG||Storage||PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.|
|Immunogen||STMN3 fusion protein ag1853||Full name||stathmin-like 3|
|BC009381||Gene ID (NCBI)||50861|
Stathmin family phosphoproteins participate in the control of microtubule dynamics and have been proposed to be involved in the control of neuronal differentiation. Neuron specific Stathmin-3 (STMN3) is a novel STAT3 (signal transducer and activator of transcription 3) interacting protein. STAT3 is a key contributor to cancer cell migration and invasion. STMN3 exhibits microtubule-destabilizing activity, which is antagonized by STAT3. SCG10 is a widely studied and recognized neuronal differentiation marker, STMN3 is a SCG10-like protein (SCLIP) and is present from the earliest stages of hippocampal neuron differentiation in culture at vesicle-like structures following dynamic microtubules. RNAi mediated inhibition of this gene resulted in increased axonal branching.