SUCLG1 Antibody
Rabbit Polyclonal
Catalog number: 14923-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | mouse kidney tissue |
| Positive IHC detected in | human liver cancer |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with 14923-1-AP(SUCLG1 Antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human liver cancer using 14923-1-AP(SUCLG1 Antibody) at Dilution 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human liver cancer using 14923-1-AP(SUCLG1 Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | SUCLG1 fusion protein ag6481 | Full name | succinate-CoA ligase, alpha subunit |
|
Calculated molecular weight |
35kd |
Observed molecular
weight |
35kd |
|
GenBank accession number |
BC000504 | Gene ID (NCBI) | 8802 |
| Gene symbol | SUCLG1 | Synonyms | FLJ21114; G-ALPHA; SUCLA1 |
Background
SUCLG1(succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial) is also named as SCS-alpha and belongs to the succinate/malate CoA ligase alpha subunit family. The SUCLG1 gene encodes a 35 kDa protein with a 40 amino acids transit peptide. This enzyme catalyzes the ATP- or GTP-dependent ligation of succinate and CoA to form succinyl-CoA. Defects in SUCLG1 are the cause of mitochondrial DNA depletion syndrome type 9 (MTDPS9). This antibody is specific to SUCLG1. |
