TAF12 Antibody
Rabbit Polyclonal
Catalog number: 12353-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | ChIP, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | Y79 cells |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Y79 cells were subjected to SDS PAGE followed by western blot with 12353-1-AP(TAF12 Antibody) at dilution of 1:800
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | TAF12 fusion protein ag3017 | Full name | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
|
Calculated molecular weight |
18kd |
Observed molecular
weight |
21kd |
|
GenBank accession number |
BC011986 | Gene ID (NCBI) | 6883 |
| Gene symbol | TAF12 | Synonyms | TAF2J; TAFII20 |
Background
TAF12, also named TAF15 or TAF2J, is a TBP-associated factor that is contained in Pol I- and Pol II-specific TBP-TAF complexes, it is also a component of the transcription factor IID (TFIID) complex, which is essential for mediating regulation of RNA polymerase transcription. TAF12 plays a key role in regulating eukaryotic gene expression by directly binding promoters and enhancer-bound transactivator proteins. Likewise, TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation. |
