TAGLN Antibody
Rabbit Polyclonal
Catalog number: 10493-1-AP
Ask a question about this product click here
Loading price...
Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IF, IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse, rat |
| Positive WB detected in | mouse colon tissue, human colon tissue, human ileum tissue |
| Positive IHC detected in | human colon cancer |
| Recommended dilution | WB: 1:1000-1:10000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse colon tissue were subjected to SDS PAGE followed by western blot with 10493-1-AP(TAGLN Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human colon cancer using 10493-1-AP(TAGLN Antibody) at Dilution 1:50 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | TAGLN fusion protein ag0764 | Full name | transgelin |
|
Calculated molecular weight |
22kd |
Observed molecular
weight |
19-22kd |
|
GenBank accession number |
BC004927 | Gene ID (NCBI) | 6876 |
| Gene symbol | TAGLN | Synonyms | DKFZp686P11128; SM22; SMCC; TAGLN1; WS3-10 |
Background
The transgelin family is a group of proteins that belong to 22kd actin-related calponin superfamily. Of all three isoforms, transgelin 1 is the best characterized. Transgelin 1, also known as SM22alpha, is a specific marker for differentiated smooth muscle cells. Transgelin 2, also known as SM22 beta, is expressed by both smooth muscle and non-smooth muscle cells in a temporally and spatially regulated pattern. Trangenlin 3, also known as NP25, is only found in highly differentiated neuronal cells. This antibody was generated against full length transgelin 1 protein. It can cross-react with other two transgelins based on the sequence similarity. |
