TAGLN2 Antibody
Rabbit Polyclonal
Catalog number: 10234-2-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC, WB |
| Species specificity | human, mouse; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | human heart tissue, HEK-293 cells |
| Positive IHC detected in | human colon cancer |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human heart tissue were subjected to SDS PAGE followed by western blot with 10234-2-AP(TAGLN2 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human colon cancer using 10234-2-AP(TAGLN2 Antibody) at Dilution 1:100 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | TAGLN2 fusion protein ag0337 | Full name | transgelin 2 |
|
Calculated molecular weight |
199aa,22kd |
Observed molecular
weight |
22 kd |
|
GenBank accession number |
BC002616 | Gene ID (NCBI) | 8407 |
| Gene symbol | TAGLN2 | Synonyms | HA1756; KIAA0120 |
Background
The transgelin family is a group of proteins that belong to 22kd actin-related corpnin superfamily. Of all three isoforms, transgelin 1 is the best characterized. Transgelin 1, also known as SM22alpha, is a specific marker for differentiated smooth muscle cells. Transgelin 2, also known as SM22 beta, is expressed by both smooth muscle and non-smooth muscle cells in a temporally and spatially regulated pattern. Trangenlin 3, also known as NP25, is only found in highly differentiated neuronal cells. This antibody was generated against full length transgenlin 2 protein. It may cross react with other two transgelins based on the sequence similarity. |
