TAX1BP1 Antibody
Rabbit Polyclonal
Catalog number: 14424-1-AP
Ask a question about this product click here
Loading price...
Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse; other species not tested. |
| Cited species | |
| Positive WB detected in | HEK-293 cells, HEK-293 cells, mouse kidney tissue, mouse liver tissue, mouse lung tissue, mouse testis tissue |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with 14424-1-AP(TAX1BP1 Antibody) at dilution of 1:800
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | TAX1BP1 fusion protein ag5789 | Full name | Tax1 (human T-cell leukemia virus type I) binding protein 1 |
|
Calculated molecular weight |
91kd |
Observed molecular
weight |
68 kDa, 85 kDa |
|
GenBank accession number |
BC050358 | Gene ID (NCBI) | 8887 |
| Gene symbol | TAX1BP1 | Synonyms | CALCOCO3; T6BP; TXBP151 |
Background
TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms with MW 65-68 kDa and 86-91 kDa. Western blot analysis showed that TAX1BP1 is expressed as an 86 kDa or a 68 kDa protein. |
