TICAM2 Antibody
Rabbit Polyclonal
Catalog number: 19524-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human; other species not tested. |
| Cited species | |
| Positive WB detected in | PC-3 cells, HeLa cells, human testis tissue |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
PC-3 cells were subjected to SDS PAGE followed by western blot with 19524-1-AP(TICAM2 Antibody) at dilution of 1:500
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | toll-like receptor adaptor molecule 2 |
|
Calculated molecular weight |
27kd |
Observed molecular
weight |
32kd |
|
GenBank accession number |
NM_021649 | Gene ID (NCBI) | 353376 |
| Gene symbol | TICAM2 | Synonyms | MGC129876; MGC129877; TICAM-2; TIRAP3; TIRP; TRAM |
Background
TICAM2, also named as TIRAP3, TIRP and TRAM, is involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1. TICAM2 is involved in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS.In WB, the MW of TICAM2 is about 27-32kd. |
