Tested Applications
| Positive WB detected in | mouse brain tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 3 publications below |
Product Information
25042-1-AP targets TMCC2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag19083 Product name: Recombinant human TMCC2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-233 aa of BC131629 Sequence: MKRCRSDELQQQQGEEDGAGLEDAASHLPGADLRPGETTGANSAGGPTSDAGAAAAPNPGPRSKPPDLKKIQQLSEGSMFGHGLKHLFHSRRRSREREHQTSQDSQQHQQQQGMSDHDSPDEKERSPEMHRVSYAMSLHDLPARPTAFNRVLQQIRSRPSIKRGASLHSSSGGGSSGSSSRRTKSSSLEPQRGSPHLLRKAPQDSSLAAILHQHQCRPRSSSTTDTALLLADG Predict reactive species |
| Full Name | transmembrane and coiled-coil domain family 2 |
| Calculated Molecular Weight | 709 aa, 77 kDa |
| Observed Molecular Weight | 85-90 kDa |
| GenBank Accession Number | BC131629 |
| Gene Symbol | TMCC2 |
| Gene ID (NCBI) | 9911 |
| RRID | AB_2879866 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O75069 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
TMCC2 also termed as Cerebral protein 11 or HUCEP11 is a 709 amino acid protein, which is a multi-pass membrane protein and belongs to the TEX28 family. The TMCC2 may have an association with Alzheimer's disease.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for TMCC2 antibody 25042-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Mol Neurodegener Cognitive impairment in metabolically-obese, normal-weight rats: identification of early biomarkers in peripheral blood mononuclear cells. | ||
Hum Mol Genet Loss of TMCC2 activates endoplasm reticulum stress and causes auditory hair cell death |
