TMEM70 Antibody
Rabbit Polyclonal
Catalog number: 20388-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | A2780 cells |
| Recommended dilution | WB: 1:1000-1:10000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
A2780 cells were subjected to SDS PAGE followed by western blot with 20388-1-AP(TMEM70 Antibody) at dilution of 1:2000
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | TMEM70 fusion protein ag14226 | Full name | transmembrane protein 70 |
|
Calculated molecular weight |
260aa,29kd |
Observed molecular
weight |
18kd |
|
GenBank accession number |
BC002748 | Gene ID (NCBI) | 54968 |
| Gene symbol | TMEM70 | Synonyms | FLJ20533 |
Background
TMEM70 belongs to the TMEM70 family. It is involved in biogenesis of mitochondrial ATP synthase. Defects in TMEM70 are a cause of mitochondrial encephalocardiomyopathy neonatal due to ATP synthase deficiency (MT-ATPSD). A publication(PMID:21147908) identifies that TMEM70 gene defect as a pan-ethnic disorder and further redefines it as the most common cause of nuclear-origin ATP synthase deficiency. |
