TPI1 Antibody
Rabbit Polyclonal
Catalog number: 10713-1-AP
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Applications
| Tested applications | ELISA, WB, IP |
| Cited applications | IF, IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | Drosophila, human, mouse |
| Positive WB detected in | HepG2 cells, HEK-293 cells, A431 cells |
| Recommended dilution | WB: 1:1000-1:10000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
IP result of anti-TPI1 (10713-1-AP for IP and Detection) with 293 cell lysate.
HepG2 cells were subjected to SDS PAGE followed by western blot with 10713-1-AP(TPI1 Antibody) at dilution of 1:2000
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | TPI1 fusion protein ag1175 | Full name | triosephosphate isomerase 1 |
|
Calculated molecular weight |
27kd |
Observed molecular
weight |
27kd |
|
GenBank accession number |
BC007086 | Gene ID (NCBI) | 7167 |
| Gene symbol | TPI1 | Synonyms | MGC88108; TPI |
Background
TPI1(Triosephosphate isomerase) is also named as TIM, TPI and belongs to the triosephosphate isomerase family. It is a key enzyme in cell metabolism that controls the glycolytic flow and energy production through the interconversion of dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde 3-phosphate (G3P)(PMID:19251756). Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency). It can exsit as a homodimer(PMID:18562316). This antibody is specific to TPI1. |
