TRIM24 Antibody
Rabbit Polyclonal
Catalog number: 14208-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | HeLa cells, human heart tissue, MCF7 cells, mouse skeletal muscle tissue, L02 cells |
| Positive IHC detected in | human prostate cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HeLa cells were subjected to SDS PAGE followed by western blot with 14208-1-AP(TRIM24 Antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human prostate cancer using 14208-1-AP(TRIM24 Antibody) at Dilution 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human prostate cancer using 14208-1-AP(TRIM24 Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | TRIM24 fusion protein ag5417 | Full name | tripartite motif-containing 24 |
|
Calculated molecular weight |
117kd |
Observed molecular
weight |
116kd |
|
GenBank accession number |
BC028689 | Gene ID (NCBI) | 8805 |
| Gene symbol | TRIM24 | Synonyms | PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA; hTIF1 |
Background
TRIM24, also named as RNF82, TIF1 and TIF1A, interacts selectively in vitro with the AF2-activating domain of the estrogen receptors. Association with DNA-bound estrogen receptors, it requires the presence of estradiol. It is a regulation protein of P53. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC) wich is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. |
