TRX2,TXN2 Antibody
Rabbit Polyclonal
Catalog number: 13089-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IF, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | Raji cells, human liver tissue |
| Positive IHC detected in | human pancreas cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Raji cells were subjected to SDS PAGE followed by western blot with 13089-1-AP(TRX2,TXN2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human pancreas cancer using 13089-1-AP(TRX2,TXN2 Antibody) at Dilution 1:100 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | TRX2,TXN2 fusion protein ag3640 | Full name | thioredoxin 2 |
|
Calculated molecular weight |
166aa,18kd |
Observed molecular
weight |
12.2kd |
|
GenBank accession number |
BC013726 | Gene ID (NCBI) | 25828 |
| Gene symbol | TXN2 | Synonyms | MT-TRX; MTRX; TRX2 |
Background
TXN2(Thioredoxin-2) is also named as TRX2,MTRX,Mt-TRX and regulates the mitochondrial redox state and plays an important role in cell proliferation.It has been shown that cells conditionally deficient in Trx2 undergo apoptosis in the absence of exogenous stress, accompanied by an accumulation of intracellular ROS, the activation of caspase 9 and caspase 3, and the release of cytochrome c into the cytosol.In the retina, the expression profile and the role of Trx2 have not yet been defined(PMID:18441302).This antibody is specific to TXN2. |
