URB1-Specific Polyclonal antibody

URB1-Specific Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 20023-1-AP

Synonyms

C21orf108, KIAA0539, URB1



Tested Applications

Positive WB detected inK-562 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

20023-1-AP targets URB1-Specific in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
Calculated Molecular Weight 254 kDa
Observed Molecular Weight 240-260 kDa
GenBank Accession NumberNM_014825
Gene Symbol URB1
Gene ID (NCBI) 9875
RRIDAB_10667000
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

URB1, also named as C21orf108, KIAA0539 and NPA1, is a 2,271 amino acid protein that is homologous to the S. cerevisiae protein URB1 which is a nucleolar protein involved in the normal accumulation of 25S and 5.8S rRNAs and may also play a role in the biosynthesis of the 60S ribosomal unit. Also localized to the nucleolus, human URB1 is thought to have the same functions as S. cerevisiae URB1. The antibody is specific to URB1.

Protocols

Product Specific Protocols
WB protocol for URB1-Specific antibody 20023-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Nature

Nucleolar URB1 ensures 3' ETS rRNA removal to prevent exosome surveillance

Authors - Lin Shan
  • KD Validated