VAMP7 Antibody
Rabbit Polyclonal
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | mouse brain tissue, mouse liver tissue |
| Recommended dilution | WB: 1:500-1:5000 |
IP = Immunoprecipitation
mouse brain tissue were subjected to SDS PAGE followed by western blot with 22268-1-AP(VAMP7 Antibody) at dilution of 1:1000
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
| Immunogen | Peptide | Full name | vesicle-associated membrane protein 7 |
|
Calculated molecular weight |
25kd |
Observed molecular
weight |
20-25kd |
|
GenBank accession number |
NM_005638 | Gene ID (NCBI) | 6845 |
| Gene symbol | VAMP7 | Synonyms | SYBL1; TI-VAMP; VAMP-7 |
VAMP7, also named as SYBL1 and Ti-VAMP, belongs to the synaptobrevin family. It is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. VAMP7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. It is required for calcium regulated lysosomal exocytosis. VAMP7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. It is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. It is also required for focal exocytosis of late endocytic vesicles during phagosome formation. The antibody is specific to VAMP7. |
