VLDLR Antibody
Rabbit Polyclonal
Catalog number: 19493-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | zebra finch |
| Positive WB detected in | MCF7 cells, mouse ovary tissue |
| Recommended dilution | WB: 1:500-1:5000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
MCF7 cells were subjected to SDS PAGE followed by western blot with 19493-1-AP(VLDLR Antibody) at dilution of 1:1000
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | very low density lipoprotein receptor |
|
Calculated molecular weight |
96kd |
Observed molecular
weight |
160kd |
|
GenBank accession number |
NM_003383 | Gene ID (NCBI) | 7436 |
| Gene symbol | VLDLR | Synonyms | CHRMQ1; FLJ35024; VLDLRCH |
Background
VLDLR binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. VLDLR binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.(cytoplasmic domain of low density ipoprotein receptor). For glycosylated, the MW of VLDLR migrates to ~160kd. |
