ZHX1 Antibody
Rabbit Polyclonal
Catalog number: 13903-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | HeLa cells, HEK-293 cells, mouse heart tissue, mouse kidney tissue |
| Positive IHC detected in | human cervical cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HeLa cells were subjected to SDS PAGE followed by western blot with 13903-1-AP(ZHX1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human cervical cancer using 13903-1-AP(ZHX1 Antibody) at Dilution 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human cervical cancer using 13903-1-AP(ZHX1 Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | ZHX1 fusion protein ag4874 | Full name | zinc fingers and homeoboxes 1 |
|
Calculated molecular weight |
873aa,98kd |
Observed molecular
weight |
100-120 kDa |
|
GenBank accession number |
BC040481 | Gene ID (NCBI) | 11244 |
| Gene symbol | ZHX1 | Synonyms |
Background
Binding of the nuclear factor-Y complex (NF-Y) to the inverted CCAAT-box interferes with transcription activation through nucleosome reorganization. The three homologous proteins forming the zinc-fingers and homeoboxes (ZHX) family interact with the activation domain of NF-Ya to repress ranscription [PMID:19348505,20509910]. Human zinc-fingers and homeoboxes 1 (ZHX1) was cloned as a protein that interacts with the activation domain (AD) of the A subunit of nuclear factor-Y (NF-YA) [PMID:12237128]. |
