ZNF238 Antibody
Rabbit Polyclonal
Catalog number: 12714-1-AP
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Applications
| Tested applications | ELISA, WB, IP |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | mouse brain tissue, mouse heart tissue, mouse kidney tissue |
| Recommended dilution | WB: 1:500-1:5000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
IP result of anti-ZNF238 (12714-1-AP for IP and Detection) with mouse cerebellum tissue.
mouse brain tissue were subjected to SDS PAGE followed by western blot with 12714-1-AP(ZNF238 Antibody) at dilution of 1:1200
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | ZNF238 fusion protein ag3406 | Full name | zinc finger protein 238 |
|
Calculated molecular weight |
531aa,59kd |
Observed molecular
weight |
48 kDa |
|
GenBank accession number |
BC036677 | Gene ID (NCBI) | 10472 |
| Gene symbol | ZNF238 | Synonyms | C2H2-171; RP58; TAZ-1; ZBTB18 |
Background
ZNF238 is a member of the BTB/POZ-ZF protein family, which involve in development and cancer formation, for example BCL-6, PLZF, and HIC-1. It's a transcriptional repressor involve in myogenesis and brain development. By directly repressing the expression of two skeletal myogenesis inhibitors, ID2 and ID3, ZNF238 plays a key role in myogenesis. It can control cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Besides, ZNF238 involves in the organization of nuclear chromosomes, for its specific binding to the consensus DNA sequence that contains the E box core, and recruiting chromatin remodeling multiportein complex. ZNF238 proteins has apparent molecular masses of 60 and 48 kD |
