FMO5-specific AntibodyRabbit Polyclonal
|Tested applications||ELISA, WB, IHC|
|Species specificity||human, mouse; other species not tested.|
|Positive IHC detected in||human breast cancer|
|Recommended dilution||IHC: 1:20-1:200|
IP = Immunoprecipitation
- WB result of 16864-1-AP from Dr.Soory.
- Immunohistochemistry of paraffin-embedded human breast cancer using 16864-1-AP(FMO5-specific Antibody) at Dilution 1:50 (under 10x lens)
- Immunohistochemistry of paraffin-embedded human breast cancer using 16864-1-AP(FMO5-specific Antibody) at Dilution 1:50 (under 40x lens)
|Source||Rabbit||Purification method||Antigen affinity purification|
|Isotype||IgG||Storage||PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.|
|Immunogen||Peptide||Full name||flavin containing monooxygenase 5|
|NM_001461||Gene ID (NCBI)||2330|
Microsomal flavin-containing monooxygenases (FMOs) [dimethylaniline monooxygenase (N-oxide forming) catalyze the FAD-, NADPH- and O2-dependent oxidation of a large number of structurally diverse compounds, including drugs, pesticides, and industrial chemicals containing a soft nucleophile(PMID:12488558 ). FMO5, which belongs to the FMO family, is a lesser component of human liver microsomes and is present at about one-third the level of FMO3. FMO5 protein is also present at very low levels in kidney, however, FMO5 exhibits a severely restricted substrate specificity for most drugs and other xenobiotics examined to date(PMID:10950857). It has 2 isoforms produced by alternative splicing.